BP Yohimba 10

BP Yohimba 10 (Yohimbine HCl 10mg): Uses, Dosage & Safety

BP Yohimba 10 is a 10mg oral tablet of yohimbine hydrochloride, a bitter indole alkaloid found naturally in the bark of the yohimbe tree (Pausinystalia johimbe), native to central and western Africa. The alkaloid is combined with a hydrochloride salt to stabilise it for tablet form. Pharmacologically, yohimbine is best characterised as an alpha-2 adrenergic receptor antagonist — and that single mechanism explains both its investigated fat-loss use and its safety profile.

What you’ll learn in this article:

1. How yohimbine works by blocking alpha-2 receptors to raise sympathetic “fight-or-flight” activity and mobilise fat.
2. What the actual human evidence supports for body fat and for erectile function — and how modest it is.
3. The doses used in research, the documented cardiovascular safety concerns, and the South African regulatory position.

Key Takeaways

• Active: yohimbine hydrochloride, 10mg oral tablet, Body Pharm-branded.
• Mechanism: an alpha-2 adrenergic antagonist that increases sympathetic nervous-system output and noradrenaline release.
• Fat-loss evidence: in a small 21-day trial in 20 male athletes, 20mg/day reduced body-fat percentage (roughly 9.3% to 7.1%) without muscle-mass loss — a single small study, not proof of a large effect.
• Mechanistic support: oral yohimbine has been shown to raise plasma glycerol and free fatty acids (markers of fat mobilisation) in fasting men.
• Erectile function: a meta-analysis of seven randomised trials found yohimbine more effective than placebo for erectile dysfunction, with infrequent adverse events.
• Safety: yohimbine-containing products have caused tachycardia, high blood pressure, anxiety and gastrointestinal upset; it is associated with arrhythmia and raised blood pressure, and should not be combined with MAOI or tricyclic antidepressants.
• Regulatory: not registered with the South African Health Products Regulatory Authority (SAHPRA). Treat it as a research compound.

What Is BP Yohimba 10?

BP Yohimba 10 is an oral tablet containing 10mg of yohimbine HCl. Yohimbine is a naturally occurring alkaloid — a bitter-tasting plant compound — concentrated in the bark of the yohimbe tree. Regardless of its botanical source, the isolated hydrochloride salt behaves as a defined pharmacological agent rather than a vague “herbal extract,” which is why its effects and risks are relatively well studied.

• Format: 10mg oral tablet, taken by mouth (no reconstitution needed).
• Active: yohimbine hydrochloride.
• Studied for: stubborn-fat loss and erectile function.
• Status: research compound; sits in the weight-loss tablets range, in a separate regulatory tier from any registered medicine.

How Yohimbine Works: The Alpha-2 Mechanism

Yohimbine’s effects trace back to one action: it is an alpha-2 adrenergic receptor antagonist. Alpha-2 receptors normally act as a brake on the sympathetic nervous system; by blocking them, yohimbine releases that brake, increasing sympathetic “fight-or-flight” output and the release of the catecholamines noradrenaline and adrenaline.

On fat cells, catecholamines bind adrenergic receptors in a lock-and-key fashion and can trigger the breakdown of stored fat (lipolysis). Fat cells also carry alpha-2 receptors that normally restrain this process, so an alpha-2 blocker can, in theory, tip the balance toward fat release. This is more than theory: in healthy men, oral yohimbine raised circulating glycerol and free fatty acids — direct markers of fat mobilisation. Notably, that effect was measured in fasting subjects, which is the pharmacological rationale behind taking it before fasted cardio: insulin from a recent meal suppresses lipolysis and blunts the response.

The same sympathetic activation that mobilises fat also raises heart rate and blood pressure — the mechanism and the main risks are two sides of the same coin, so the safety section below is not optional reading.

What the Evidence Shows

Body fat. The most-cited human trial randomised 20 male soccer players to yohimbine or placebo for 21 days. The yohimbine group, dosed at 20mg per day, significantly reduced body-fat percentage (about 9.3% down to 7.1%) with no loss of muscle mass and no change in performance measures (Ostojic, Research in Sports Medicine, 2006). This is genuinely supportive — but it is one small, short study in lean, trained men. It should be read as a promising signal, not as evidence of a large or guaranteed effect in the general population.

Erectile function. Yohimbine has a longer research history for erectile dysfunction. A systematic review and meta-analysis of seven randomised trials (419 men) found yohimbine superior to placebo for erectile dysfunction, with uncommon and reversible adverse events (Ernst & Pittler, Journal of Urology, 1998). It predates modern PDE5 inhibitors (such as sildenafil) and is not a first-line therapy, but the controlled evidence for this use is stronger than for fat loss.

A fair objection: “If it lowers body fat and helps erections, why isn’t it a mainstream drug?” Because the effect sizes are modest, the trials are small or dated, and the cardiovascular side-effect profile limits who can safely use it. The pharmacology is real; the case for it as a broad, low-risk fat-loss aid is not.

Dosage (Research Use)

The doses with human data behind them are modest. The body-composition trial above used 20mg per day, split into two doses, for 21 days. In practice, users of a 10mg tablet often take a single tablet about 30 minutes before fasted cardio, on the fat-mobilisation rationale described above. The figures here reflect the studied regimen and common practice — they are not a medical recommendation, and individual tolerance varies widely.

• Studied dose: 20mg/day (two divided doses) in the 21-day trial.
• Common practical use: one 10mg tablet, ~30 minutes before fasted cardio.
• Timing rationale: taken fasted because a recent meal (and the insulin it triggers) blunts the fat-mobilising response.
• Sensitivity: yohimbine is a potent stimulant; start low, and never stack it with other stimulants without understanding the additive cardiovascular load.

A frequent assumption: “More will burn more fat.” No — the dose-limiting problems (anxiety, racing heart, blood-pressure spikes) scale faster than any extra fat-loss benefit, and higher doses are exactly where the serious adverse events cluster.

Side Effects and Safety Profile

Because yohimbine drives sympathetic activation, its side effects are predictable — and, at higher doses, potentially serious. A review of poison-control reports found that yohimbine-containing products caused tachycardia, elevated blood pressure, agitation/anxiety and gastrointestinal upset, and that callers were more likely than average to require medical evaluation (Kearney et al., Annals of Pharmacotherapy, 2010).

Government safety guidance is blunt about the cardiovascular risk. Yohimbine has been associated with cardiac arrhythmia, blood-pressure problems, heart attacks and seizures, and should not be combined with MAOI or tricyclic antidepressants; it is also advised against in pregnancy and breastfeeding. On mechanism alone, anyone with high blood pressure, a heart condition, an anxiety disorder, or who is on antidepressants should avoid it.

• Common: rapid heartbeat, raised blood pressure, anxiety/jitteriness, sweating, nausea.
• Serious (dose-related): arrhythmia, hypertensive episodes, and, in overdose, seizures.
• Avoid if: you have hypertension or cardiovascular disease, an anxiety or panic disorder, or take MAOIs or tricyclic antidepressants; and in pregnancy or breastfeeding.
• Interactions: additive with other stimulants (caffeine, ephedrine-type compounds) — the combined cardiovascular strain is the main danger.

A reasonable question: “It’s plant-derived — doesn’t that make it gentle?” No. Botanical origin says nothing about safety; the isolated alkaloid is a potent cardiovascular stimulant, which is precisely why the contraindications above matter.

Regulatory Status in South Africa

Yohimbine is not a SAHPRA-registered medicine in South Africa. Under the SAHPRA framework, complementary medicines and health supplements must be registered, are held to quality and safety standards, and may only carry low-risk, general-health claims — not disease-treatment claims. A product sold outside that registered framework cannot lawfully be marketed as a treatment.

• SAHPRA status: no local registration; supplied as a research compound only.
• Claims: it is not approved to treat obesity, erectile dysfunction, or any other condition in South Africa.
• Practical step: consult a registered South African healthcare practitioner before use, particularly if you have any cardiovascular history or take other medication.

Why Buy BP Yohimba 10 from Beskinny?

BP Yohimba 10 is stocked at Beskinny at R220 per unit, shipped from a South African warehouse with tracked courier delivery to all major metros.

• Product spec: 10mg yohimbine HCl oral tablets, Body Pharm branded.
• Current stock: see the live count on the product page, which is the source of truth.
• Why Beskinny: a dedicated South African fat-loss and research-compound retailer with a narrow, fast-moving weight-loss tablets range, not a general supplement reseller.

Order BP Yohimba 10 at R220. Check live stock and add to cart on the Beskinny product page.

Frequently Asked Questions

Does yohimbine actually burn fat?

There is real but limited human evidence. In one small 21-day trial, 20mg/day reduced body-fat percentage without muscle loss, and oral yohimbine is known to raise markers of fat mobilisation in fasting men. The effect is modest and best supported alongside training and a calorie deficit — not a stand-alone fat burner.

Why take it before fasted cardio?

Yohimbine’s fat-mobilising action is blunted by insulin, so it was studied and is typically used in a fasted state. The rise in free fatty acids was measured in fasting subjects, which is the basis for the pre-fasted-cardio timing.

What are the main side effects?

Most commonly a fast heartbeat, raised blood pressure, anxiety and stomach upset. More serious cardiovascular events are possible, especially at higher doses, so anyone with heart or blood-pressure problems should avoid it.

Who should not take yohimbine?

Avoid it if you have hypertension or heart disease, an anxiety disorder, or take MAOI or tricyclic antidepressants, and during pregnancy or breastfeeding. Discuss any personal use with a registered SA practitioner first.

Is BP Yohimba 10 legal to buy in South Africa?

Yohimbine is not registered with SAHPRA, so it cannot be marketed as a treatment for any condition. Beskinny supplies it as a research compound only.

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Next step: Check live stock and pricing on the Beskinny product page, and speak to a registered SA practitioner before first use if you have any cardiovascular history.

References

1. Yohimbine: the effects on body composition and exercise performance in soccer players. Research in Sports Medicine (Ostojic), 2006.
2. Alpha 2-antagonist compounds and lipid mobilization: evidence for a lipid mobilizing effect of oral yohimbine in healthy male volunteers. European Journal of Clinical Investigation (Galitzky et al.), 1988.
3. Yohimbine. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury, NIDDK, 2020.
4. Yohimbine for erectile dysfunction: a systematic review and meta-analysis of randomized clinical trials. Journal of Urology (Ernst & Pittler), 1998.
5. Adverse drug events associated with yohimbine-containing products: a retrospective review of the California Poison Control System reported cases. Annals of Pharmacotherapy (Kearney et al.), 2010.
6. Yohimbe: Usefulness and Safety. National Center for Complementary and Integrative Health (NIH), 2025.
7. Complementary Medicines. South African Health Products Regulatory Authority (SAHPRA), 2026.